Coding

Part:BBa_K364303:Design

Designed by: Katalin Sandor   Group: iGEM10_Debrecen-Hungary   (2010-08-12)

DAF-12 LBD


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Compatible Rfc 25 and Rfc 10.


Source

Caenorhabditis elegans nuclear receptor DAF-12.

References

Antebi A, Yeh WH, Tait D, Hedgecock EM, Riddle DL. daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes Dev. 2000 Jun 15;14(12):1512-27.

Snow MI, Larsen PL.Structure and expression of daf-12: a nuclear hormone receptor with three isoforms that are involved in development and aging in Caenorhabditis elegans. Biochim Biophys Acta. 2000 Nov 15;1494(1-2):104-16.

Matyash V, Entchev EV, Mende F, Wilsch-Bräuninger M, Thiele C, et al. (2004) Sterol-Derived Hormone(s) Controls Entry into Diapause in Caenorhabditis elegans by Consecutive Activation of DAF-12 and DAF-16. PLoS Biol 2(10): e280.

Motola D.L., Cummins C.L., Rottiers V., Sharma K.K., Li T., Li Y., Suino-Powell K., (...), Mangelsdorf D.J. Identification of Ligands for DAF-12 that Govern Dauer Formation and Reproduction in C. elegans. (2006) Cell, 124 (6), pp. 1209-1223.